The contraceptive agent results in inhibition of the activin-stimulated re-lease of FSH, thereby resulting in a de-crease in fertility and facilitating contra-ception in the patient. This invention relates to contraception. The biosyntllesis and secretion of 15 FSH within the anterior pituitary is controlled through the complex interaction of several h- -. Inhibin And follistatin have the ability to inhibit the synthesis and secretion of FSH by the pituitary De Jong et al. Both activin and inhibin subunits have been isolated from natural sources. In Mason et al. The use of activin to increase fertility in a male mammal is described in Attie et al.
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